Boston University School of Medicine :Whitaker Cardiovascular Institute (Kenneth Walsh)
Awareness of and Attitudes Toward User Involvement in Research
Impact of standard supply of care on receiving smoking cessation recommendation: Korean Nationwide Well being Panel information evaluation
Background: Regardless of varied anti-smoking insurance policies, the smoking charge in adults continues to be excessive in Korea. Docs’ recommendation is understood to extend the smoking cessation success charge. Nevertheless, few research have reported the impact of getting a standard supply of care (USC) on receiving smoking cessation recommendation.
Goal: To find out the impact of USC on receiving smoking cessation recommendation.
Strategies: We carried out a number of panel logistic regression analyses to establish the impact of getting a USC on the speed of receiving a health care provider’s smoking cessation recommendation utilizing 2009, 2012 and 2013 datasets from the Korea Well being Panel database. Solely individuals who responded to questions relating to a USC and smoking cessation recommendation have been analysed. Finally, 5243 observations have been included within the last evaluation.
Outcomes: A better proportion of individuals with a USC obtained smoking cessation recommendation from medical doctors (58.4% in 2009, 64.0% in 2012 and 59.6% in 2013) than these not having a USC (28.6% in 2009, 37.5% in 2012 and 34.8% in 2013). The chances ratios (ORs) of receiving smoking cessation recommendation in folks with a USC have been greater than these of individuals with no USC after performing a number of panel logistic regression evaluation with random results (OR: 2.24; 95% confidence interval: 1.90-2.63).
Conclusions: Having a USC elevated the chances of receiving a health care provider’s smoking cessation recommendation in Koreans. The outcomes of this research counsel {that a} well being care coverage that encourages having a USC is beneficial in receiving extra smoking cessation recommendation in a Korean inhabitants.
Mouse Monoclonal Anti-Gardasil vaccine L1s (Human Papilloma Virus/HPV6+11+16+18 late proteins) antiserum control for ELISA
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike Protein RBD is urgently needed to accelerate the development of COVID-19 vaccines.
Description: Rabies virus (RABV), scientific name Rabies lyssavirus, is a deadly neurotropic virus that causes rabies in humans and animals. Rabies virus has an extremely wide host range and its transmission most often occur through the saliva of animals. Without intervention prior to disease progression, rabies has the highest case fatality of any infectious disease. RABV contains a single-stranded negative-sense R genome that encodes five structural proteins: nucleoprotein (N), phosphoprotein (P), matrix protein (M), glycoprotein (G), and R-dependent R polymerase (L). Among these viral proteins, the RABV glycoprotein (RABV-G) is a pivotal player mediating virus entry and the major target of neutralizing antibodies, thus a key factor for vaccine and drug design.A rapid and effective assay kit detecting the levels ofRABV-G is urgently needed to accelerate the development of RABV vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike RBD is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike Trimer is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike Trimer is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike S1 is urgently needed to accelerate the development of COVID-19 vaccines.
SARS-CoV-2 Spike RBD (B.1.1.529) Specific ELISA Kit (For Vaccine Development)
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
SARS-CoV-2 Spike RBD (B.1.617.2) Specific ELISA Kit (For Vaccine Development)
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
SARS-CoV-2 Spike Trimer (B.1.1.529) Specific ELISA Kit (For Vaccine Development)
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
SARS-CoV-2 Spike Trimer (BA.4) Specific ELISA Kit (For Vaccine Development)
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
SARS-CoV-2 Spike Trimer (BA.5) Specific ELISA Kit (For Vaccine Development)
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: Varicella-zoster virus (VZV) the etiologic agent of chickenpox and herpes zoster [HZ], is highly contagious and still endemic worldwide. Glycoprotein E (gE) is one of the known glycoproteins (gB, gC, gE, gH, gI, gK, gI) of VZV that is most abundantly expressed on the surface of virus and infected cells, playing an important role in viral replication and cell-to-cell spread. The strongly immunogenic gE can provide strong IgG signal in body fluid, which makes it ideal to be developed as an antigen for analysis of Immunogenicity in the development of VZV vaccine.Therefore,It's helpful to develop the Varicella Zoster Virus Glycoprotein E (VZV gE) ELISA Kit to quantitative detection the VZV gE antigen in vaccine samples during the manufacture and quality control of vaccine development.
Description: Respiratory syncytial virus (RSV) is a highly contagious virus causing severe infection in infants and the elderly. Various approaches are being used to develop an effective RSV vaccine. The RSV fusion (F) subunit, particularly the cleaved trimeric pre-fusion F, is one of the most promising vaccine candidates under development.A rapid and effective assay kit detecting the levels of HRSV (A) Pre-Fusion glycoprotein F0 is urgently needed to accelerate the development of RSV vaccines.
Description: Most in vitro RSV neutralizing antibodies in human sera are directed against the prefusion conformation, but due to its instability the prefusion conformation has a propensity to prematurely refold into the stable postfusion conformation, both in solution and on the surface of the virions. An RSV F protein that has both high expression levels and maintains a stable prefusion conformation would, therefore, be a promising subunit vaccine candidate against RSV. To facilitate the RSV-related research, drug trials and vaccine development,a rapid and effective assay kit detecting the specific levels of HRSV (A) Post-Fusion glycoprotein F0 is urgently needed to accelerate the development of RSV vaccines.
Custom Testing of Samples for Antibodies (IgA/IgG/IgM) to West Nile Virus vaccines (WNV-ENV/NS1/prM) vaccine by ELISA
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has posed a serious threat to human health. A rapid and effective assay kit detecting the levels of SARS-CoV-2 Spike protein is urgently needed to accelerate the development of COVID-19 vaccines.
Description: Mumps virus (strain Miyahara vaccine) (MuV) HN Protein, His Tag (HNN-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 106 - Thr 582 (Accession # P11235).
Consciousness of and Attitudes Towards Consumer Involvement in Analysis on Getting older and Well being: Protocol for a Quantitative Massive-Scale Panel Research
Background: Consumer involvement is a requirement of most analysis funders. There’s a rising physique of literature exploring the advantages and challenges of consumer involvement in analysis, however such research are scarce within the area of growing older and well being.
Furthermore, the vast majority of such analysis is qualitative, which limits the generalizability of outcomes. The UserAge panel research can be instrumental in increasing information that can profit the standard and affect of consumer involvement in future analysis.
Goal: The intention of this research is to find out the attention and understanding of and attitudes towards consumer involvement in analysis amongst totally different classes of information customers and researchers over time.
Strategies: A panel research can be carried out with three totally different classes of information customers (folks aged 60 years and older, casual carers, and professionals in well being care and structure) and researchers in growing older and well being.
An expert survey firm will acquire information from all samples in parallel. Potential individuals can be requested to full the survey through phone or on-line, or individuals can request a paper survey to be despatched to them within the put up. A draft set of questions on attitudes and behavioral patterns associated to analysis utilization and consumer involvement in analysis was compiled based mostly on current literature and enter from the analysis crew.
Utilizing a participatory method, we engaged a consumer discussion board, the place Eight older folks and three researchers collectively refined the survey for time/size to finish, terminology, readability, and context. Knowledge collected through the web or phone can be robotically processed, and information collected on paper types can be entered in machine-readable types.
The survey firm will retailer all information and ship the quality-controlled database to the college for additional storage. Analyses of frequencies and measures of central tendency can be used for descriptive functions. To check teams, state-of-the artwork statistical analyses can be used.
Outcomes: Knowledge assortment for the primary research wave began in September 2019 and can be accomplished in spring 2020. Knowledge can be prepared for evaluation following cleansing and high quality management, which began throughout summer time 2020 and can be accomplished autumn 2020. We anticipate the info assortment for the second research wave to start out in September 2021.
Conclusions: That is the primary quantitative large-scale panel research specializing in developments in attitudes towards, consciousness of, and information about consumer involvement in analysis on growing older and well being in Sweden. The outcomes will generate new and necessary information to advance the understanding of consumer wants and preferences in addition to the relevance of consumer involvement in analysis on growing older and well being.
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.
Description: To serve as a true negative control for various procedures, this monoclonal IgG should be used under the identical conditions and at the same dilution as the rabbit monoclonal antibody being used for a positive reaction.
Paraffin Tissue Section Panel - Human Tumor, Different Tumor Type, Different Donors, Panel I, 5 tissue spots